We hypothesized that besides these quantitative tr However, it is currently unknown wh View research View latest news Sign up for updates. Authors: Jeffrey D Lifson. Published on: 24 December The host factor lens epithelium-derived Evolution and gene capture in ancient endogenous retroviruses - insights from the crocodilian genomes Crocodilians are thought to be hosts to a diverse and divergent complement of endogenous retroviruses ERVs but a comprehensive investigation is yet to be performed. IFITM proteins are incorporated onto HIV-1 virion particles and negatively imprint their infectivity Interferon induced transmembrane proteins 1, 2 and 3 IFITMs belong to a family of highly related antiviral factors that have been shown to interfere with a large spectrum of viruses including Filoviruses, Co Published on: 15 February
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Authors: Jeffrey D Lifson. Published on: 14 December Published on: 10 February The Erratum to this article has been published in Retrovirology 12 Published on: 12 December
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|Content type: Short report. The dynamic interaction between HIV and its host governs the replication of the virus and the study of the virus-host interplay is key to understand the viral lifecycle.
Macrophages are key targets of HIV-1 infection. However, it is currently unknown wh Published on: 3 February
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Following translation, HIV-1 Rev localizes to the nucleus and bi In vitro activity of dolutegravir against wild-type and integrase inhibitor-resistant HIV-2 Dolutegravir recently became the third integrase strand transfer inhibitor INSTI approved for use in HIV-1—infected individuals. Published on: 23 December Long-acting nanoformulated antiretroviral therapy nanoART is designed to improve patient regimen adherence, reduce systemic drug toxicities, and facilitate clearance of human immunodeficiency virus type one Computational modeling suggests dimerization of equine infectious anemia virus Rev is required for RNA binding The lentiviral Rev protein mediates nuclear export of intron-containing viral RNAs that encode structural proteins or serve as the viral genome.
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|Citation: Retrovirology 12 Friend retrovirus drives cytotoxic effectors through Toll-like receptor 3 Pathogen recognition drives host defense towards viral infections. Evolution and gene capture in ancient endogenous retroviruses - insights from the crocodilian genomes Crocodilians are thought to be hosts to a diverse and divergent complement of endogenous retroviruses ERVs but a comprehensive investigation is yet to be performed. Published on: 31 December Authors: Jeffrey D Lifson.
Caveolin-1 mediated uptake via langerin restricts HIV-1 infection in human Langerhans cells Human Langerhans cells LCs reside in foreskin and vaginal mucosa and are the first immune cells to interact with HIV-1 during sexual transmission.
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More about our metrics. Editorial Board Sign up for article alerts and news from this journal. Vpr is one of the most enigmatic viral auxiliary proteins of HIV.
HIV-1 formation is driven by the viral structural polyprotein Gag, which assembles at the plasma membrane into a hexagonal lattice. HIV-1, like all viruses, is entirely dependent on the host cell for providing the metabolic resources for completion of the viral replication cycle and the production of virions. Published on: 15 February
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|We hypothesized that besides these quantitative tr Citation: Retrovirology 11 Authors: Leen Mathys and Jan Balzarini.
Content type: Commentary. Published on: 31 January Published on: 2 February More about our metrics.